Ali Akbar Velayati, a senior advisor to Leader of the Islamic Revolution Ayatollah Seyyed Ali Khamenei on international affairs, made the remarks in a conference on Islamic unity in the Iraqi capital, Baghdad, on Saturday.
Velayati said the Americans and Arabs are trying to create a new Middle East, whose reality will be marked by the disintegration of Muslim societies.
He said Washington was seeking to split Syria through its presence in the eastern Euphrates.
He also referred to US Secretary of State Rex Tillersons recent Middle East tour, saying the visit had been aimed at broadening the division among the Muslim Ummah and Muslim countries.
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Velayati said the Americans were seeking to establish bases for the NorthAtlantic Treaty Organization (NATO) with the help of Muslim states to prevent unity among these countries.
The Americans and Zionists should know that as they were defeated in the Lebanon, Syria, and Iraq, their illusions wont materialize. The resistance front in Iraq, Syria, and Lebanon will push them out of the eastern Euphrates, he said.
Much of northeast Syria to the east of the Euphrates is controlled by the so-called Syrian Democratic Forces (SDF), which is dominated by the militants from the Kurdish Peoples Protection Units (YPG) and is backed by the US.
The US announced last month that it would work with the SDF to set up a new 30,000-strong border security force along the Turkish border with Iraq and within Syria along the Euphrates River.
